Coping with the metabolic stress of leaving home

摘要：

Detachment from extracellular matrix causes metabolic defects that transformed cells must overcome in order to survive and proliferate outside of their normal niche.A recent report from Jiang et al.published in Nature describes how cancer cells grown in suspension utilize reductive carboxylation of glutamine to transfer reducing power from the cytosol to mitochondria to detoxify reactive oxygen species and promote anchorage-independent growth and survival.

所属期刊栏目：26

在线出版日期：2016-08-16（万方平台首次上网日期，不代表论文的发表时间）

页码：757-758