Killing me softly: microparticles target deformable cells
Mechanical deformability is known to increase during cancer progression.Now Ma et al.identify a therapeutic strategy that targets deformable cells by microparticle-based drug delivery.Cancer cells tend to be softer than normal cells ”1,2”.Cells with increasing malignant potential ”3-4”,and expressing activated oncogenes such as Kras ”1”,have reduced cortical tension and increased mechanical deformability relative to control cells.
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2016-07-14(万方平台首次上网日期,不代表论文的发表时间)
637-638