Mex3B: a coreceptor to present dsRNA to TLR3

摘要：

Toll-Like Receptors (TLRs) play critical roles in the early innate immune response to invading pathogens by sensing microorganisms;a number of accessory molecules have been shown to assist microbial recognition by TLRs.In a recent paper in Cell Research,Yang et al.demonstrate that Mex3B is associated with TLR3 in the endosomes and promotes dsRNA binding and proteolytic processing of TLR3,suggesting that Mex3B acts as a coreceptor of TLR3 in response to dsRNA.

所属期刊栏目：26

在线出版日期：2016-05-09（万方平台首次上网日期，不代表论文的发表时间）

页码：391-392