The quest for spatio-temporal control of CAR T cells
Chimeric antigen receptors (CARs) are synthetic receptors capable of directing potent antigen-specific anti-tumor T cell responses.A recent report by Wu et al.extends a series of strategies aiming to curb excessive T cell activity, utilizing in this instance a chemical dimerizer to aggregate antigen-binding, T cell-activating and costimulatory domains.
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2016-01-21(万方平台首次上网日期,不代表论文的发表时间)
1281-1282