Probing hepatocyte heterogeneity
To maintain homeostasis, organs replace cells lost through normal cellular turnover, often through the straightforward replication of exist ing cells.A recent paper in Nature shows that cells in the liver are not equivalent when it comes to their replicative capacity;rather, a sub set of hepatocytes defined by the maintenance of active Wnt signaling bears the brunt of responsibility for maintaining liver mass.
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2015-12-10(万方平台首次上网日期,不代表论文的发表时间)
1181-1182