Cutting in on a secretase pas de deux
Two proteolytic enzymes,β-and γ-secretases,work together to produce the amyloid β-peptide of Aizheimer”s disease.New evidence suggests that these proteases directly interact and compounds that disrupt this interaction reduce amyloid β-peptide levels without directly blocking either enzyme”s solo activity.
25
2015-11-25(万方平台首次上网日期,不代表论文的发表时间)
1091-1092