Opposing roles of conventional and novel PKC isoforms in Hippo-YAP pathway regulation
Dear Editor,The Hippo-YAP pathway is an evolutionally conserved signaling module that controls tissue growth during development and its dysregulation causes cancer ”1”.Core components of the Hippo pathway include a kinase cascade comprising MST1/2 and LATS1/2 kinases,in which MST1/2 phosphorylates and activates LATS1/2 ”2”.
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This work was supported by NIH grants GM51586 and EY022611 to KLG,and GM7752 to AWH and SWP and the National Natural Science Foundation of China 31030019,YX.
2015-09-24(万方平台首次上网日期,不代表论文的发表时间)
985-988