Pseudouridine in a new era of RNA modifications
Two articles recently published in Nature and Cell report the first transcriptome-wide maps of pseudouridine (Ψ) at single-base resolution through selective chemical labeling,suggesting new mechanisms and functions ofΨ in mRNA and noncoding RNA molecules.Pseudouridine (Ψ) was among the first post-transcriptional modifications discovered and is overall one of the most abundant ”1”.It is present in a wide range of cellular RNAs and is highly conserved across species.
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2015-03-18(万方平台首次上网日期,不代表论文的发表时间)
153-154