H3K4me3 epigenomic landscape derived from ChIP-Seq of 1000 mouse early embryonic cells

摘要：

Dear Editor,Epigenetic regulation is crucial to the establishment and maintenance of the identity of a cell.Recent studies suggest that transcription is implemented amongst a mixture of various histone modifications ”1”.It has also been recognized that to interrogate function of genetic information,comprehensively systematic profiling of the epigenome in multiple cell stages and types is required ”2”.Chromatin immunoprecipitation (ChIP) has become one of the most critical assays to investigate the complex DNA-protein interactions ”3”.

所属期刊栏目：25

资助基金：This work was supported by the Ministry of Science and Technology of China 2011CB809106,2012CB966704 and the National Natural Science Foundation of China 21222501,21327808,31271543,91313302.

在线出版日期：2015-02-06（万方平台首次上网日期，不代表论文的发表时间）

页码：143-147