MicroRNA-155 broadly orchestrates inflammation-induced changes of microRNA expression in breast cancer

摘要：

Dear Editor,
During the last decades,a number of key mediators of inflammation-induced tumorigenesis have been identified to support tumor progression in response to inflammation stimulation [1].Recent studies show that a few cancerrelated microRNAs (miRNAs) are modulated by inflammation signals [2,3],implicating miRNAs as a new class of mediators between inflammation and cancer.However,how inflammation regulates miRNAs in cancer cells and how such miRNA mediators function in inflammationassociated tumorigenesis remain largely unexplored.miRNA-155 (miR-155) has been documented as one of the most prominent miRNAs linking inflammation to cancer [4].

所属期刊栏目：24

资助基金：grants from the Ministry of Science and Technology of China2011CB811303,2012CB910802,2014CB964802;the National Natural Science Foundation of China91219306,31270840,31170754,30970621

在线出版日期：2014-03-20（万方平台首次上网日期，不代表论文的发表时间）

页数：共4页

页码：254-257