Exo-endo trans splicing: a new way to link
In addition to canonical cis splicing,which joins exons from a single pre-mRNA,various forms of trans splicing have been described,whereby two separate precursor transcripts are linked with each other.A new study by Hu et al.in Cell Research characterizes a novel and unusual splicing variation,called exo-endo trans splicing.
A recent study from Bo-Liang Li's group published in Cell Research [1] describes a novel type of trans splicing:an exogenous plasmid-derived RNA transcript is joined in trans with an endogenous mRNA,generating a chimeric mRNA that encodes a functional protein.Therefore,the authors have termed this unusual mRNA processing event exo-endo trans splicing.
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2013-10-23(万方平台首次上网日期,不代表论文的发表时间)
共2页
1071-1072