Monoclonal antibody against CXCL-1O/IP-1O ameliorates influenza A (H1N1) virus induced acute lung injury

摘要：

Dear Editor,
Most patients infected with 2009 swine-origin influenza A (H1N1) virus (S-OIV) suffered respiratory illness.Some severely infected patients developed acute lung injury (ALI) and even acute respiratory distress syndrome (ARDS),which is the predominant cause for reported deaths [1].After the pandemic,an analysis of data from flu cases in adults and children living in Wisconsin state of USA concluded that the symptoms and risk of complications from 2009 H1N1 swine flu was not greater compared with either H1N1 or H3N2 seasonal flu [2].The H1N1 pandemic flu was not linked to substantially more hospitalization or pneumonia than these recent seasonal flu strains [2].However,a recent study estimated that the mortality associated with the 2009 H1N1 swine flu was 15 times higher than the World Health Organization (WHO) reported [3],confirming that the 2009 S-OIV outbreak was a pandemic.

所属期刊栏目：23

资助基金：the Ministry of Science and Technology of China2009CB522105;the National Natural Science Foundation of China81030032,81230002;the 111 Project B08007.CJ is a Hsien Wu professor of Biochemistry

在线出版日期：2013-07-24（万方平台首次上网日期，不代表论文的发表时间）

页数：共4页

页码：577-580