Dendritic self-avoidance: protocadherins have it covered
The ability of the mammalian brain to accurately encode and process information depends on the formation of highly precise wiring of dendritic and axonal processes.One important principle of dendrite and axon organization is termed self-avoidance,which refers to the tendency of branches from the same cell (or sister branches) to spread from one another with minimal crossing or overlap [1].Self-avoidance ensures that dendritic territories are covered completely and yet non-redundantly (Figure 1).Conversely,arbors from different neurons can overlap freely with one another,or co-exist.
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2013-05-02(万方平台首次上网日期,不代表论文的发表时间)
共3页
323-325