In vitro generation of platelets through direct conversion:first report in My Knowledge (iMK)

摘要：

Blood transfusion medicine requires a constant supply of platelets,which is now totally donor dependent.Recent advances in the generation of platelets in vitro through megakaryocytes (MKs) may provide protocols not only via pluripotent stem cells,including induced pluripotent stem cells (iPSCs) and embryonic stem cells (ESCs),but also via induced MKs (iMKs).For the first time,mouse and human fibroblasts are successfully transdifferentiated into iMKs by the introduction of three factors,p45NF-E2,Maf G,and Maf K.

所属期刊栏目：23

在线出版日期：2013-04-08（万方平台首次上网日期，不代表论文的发表时间）

页数：共3页

页码：176-178