RNAi screening of the human colorectal cancer genome identifies multifunctional tumor suppressors regulating epithelial cell invasion
Dear Editor,
Genomic sequencing of human tumor-derived DNA has identified a vast number of novel tissue-specific genetic mutations occurring at varying frequencies [1].Frequently mutated genes are informally referred to as driver alterations (or candidate cancer genes,CAN-genes),whereas those less frequently mutated are considered passenger alterations [1,2].
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Q2-06
2012-12-28(万方平台首次上网日期,不代表论文的发表时间)
1605-1608