What comes first: translational repression or mRNA degradation? The deepening mystery of microRNA function

摘要：

While many mechanisms have been proposed for microRNAs (miRNAs) function,most ultimately cause message degradation.A view has emerged that miRNAs silence gene expression by promoting the association of mRNA decay factors.Recent research results,however,suggest that in both zebrafish and fruit fly,translational inhibition is the initiating event of miRNA-mediated gene silencing.

机标关键词：research results、gene expression、gene silencing

所属期刊栏目：22

分类号：Q2(细胞生物学)

在线出版日期：2012-12-12（万方平台首次上网日期，不代表论文的发表时间）

页码：1322-1324