Leucyl-tRNA synthetase: double duty in amino acid sensing

摘要：

The cellular response to amino acids is controlled at the molecular level by TORC1.While many of the elements that participate in TORC1 signaling are known,we still have no clear idea how cells sense amino acids.Two recent studies found that leucyltRNA synthetase (LRS) is a leucine sensor for TORC1,in both yeast and mammalian cells.

机标关键词：amino acids、leucyltRNA synthetase、mammalian cells

所属期刊栏目：22

分类号：Q2(细胞生物学)

在线出版日期：2012-11-16（万方平台首次上网日期，不代表论文的发表时间）

页码：1207-1209