The inflammasome: A remote control for metabolic syndrome

摘要：

Humans can be divided into roughly three groups with distinct microbial communities in their gastro-intestinal tract.The microbiota contributes to metabolic activity in the gastrointestinal tract of the host,but what mechanisms shape the composition of the gut microbiota,and how does a person's ‘enterotype' affect metabolic processes in distant organs? Flavell and colleagues shed light on these questions by revealing an important role for inflammasomes in modulating the prevalence of colitogenic species,and by demonstrating that dysbiosis influences susceptibility to non-alcoholic steatohepatitis (NASH) and other manifestations of metabolic syndrome.

所属期刊栏目：22

资助基金：M Lamkanfi is supported by grants from European Union Marie-Curie256432;ERC281600;the Fund for Scientific Research G030212N,1.2.201.10.N.00 and 1.5.122.11.N.00 Flanders.T-D K is supported by grants from NIAMS/NIHR01AR056296;the American Lebanese Syrian Associated Charities

在线出版日期：2013-03-08（万方平台首次上网日期，不代表论文的发表时间）

页数：共4页

页码：1095-1098