Mapping enhancer and promoter interactions
Histone modifications have previously been leveraged to map the locations of candidate enhancer and promoters in one dimensional genomic space.Chepelev et al.report the first Chromatin Interaction Analysis with Paired-End Tag (ChlA-PET) sequencing of a specific histone modification to systematically map long-range physical interactions among enhancer and promoters,yielding insights into the nature of these interactions.
nature of
22
Q2(细胞生物学)
2012-10-29(万方平台首次上网日期,不代表论文的发表时间)
789-790