Exogenous plant MIR168a specifically targets mammalian LDLRAP1: evidence of cross-kingdom regulation by microRNA
In the initial published version of this article,an error was made during the assembly of Figure 5B.Figure 5B is a representative image of western blots,which shows that rice-derived MIR 168a can down-regulate LDLRAP 1 expression in mouse liver and that the injection of antiMIR168a rescued the expression of LDLRAP1.After the initial publishing of this article,it has been brought to our attention that the image of the internal control in previous Figure 5B showing the western blot results of α-tubulin,actually duplicated the images in other parts of the paper (specifically,the left two lanes of the αt-tubulin western data in previous Figure 5B duplicated the α-tubulin image of Figure 3C,while the right two lanes duplicated the α-tubulin image of Figure S3D).This error in previous Figure 5B was inadvertently introduced during the assembly of figure panels for this paper.Moreover,after a careful re-examination of the figure legend,we also found that the figure legend of previous Figure 5 was not precise.The corrected figure and its legend are provided below.The detailed results of all the western blot experiments analyzing liver samples of individual mice from different groups (chow diet,rice,rice +anti-ncRNA,rice + anti-MIR168a) are also available for interested readers at our website:http://mcube.nju.edu.cn/mir 168a_regulates_ldlrap1.
microRNA、Figure、western blot、image、two lanes、rice、results、initial、during、paper、individual、different、attention、analyzing、provided、version、control、parts、found、mice
22
Q2(细胞生物学)
2012-04-20(万方平台首次上网日期,不代表论文的发表时间)
273-274