New blood brothers: the GPR55 and CB2 partnership
Endocannabinoids are increasingly being recognized as key lipid-derived regulators of immune function ”1”.Although the peripheral cannabinoid type 2 receptor (CB2) is thought to orchestrate many of these actions,additional non-CB1/CB2-mediated effects ofcannabinoids have been identified in immune cells ”1,2”,where several orphan G protein-coupled receptors (GPCRs),including the effusive GPR55,are implicated ”3”.Despite numerous studies addressing the cannabinoid sensitivity of GPR55,the area remains a pharmacological minefield,with much inconsistent and conflicting data.
immune function、immune cells、receptor、thought、studies、remains、type、area、key
21
R329.2(人体形态学)
2011-12-23(万方平台首次上网日期,不代表论文的发表时间)
1391-1392