FADD: an endogenous inhibitor of RIP3-driven regulated necrosis
Thanks to the work of multiple laboratories worldwide,the classical dichotomy postulating that apoptosis and necrosis would constitute diametrically opposed cell death subroutines has recently been dismissed ”1”.Thus,approximately in the same year when immunogenic instances of apoptosis were first characterized ”2”,the traditional belief that necrosis would represent a merely accidental,unregulated cell death modality has been definitely abandoned ”3”.This has fueled an intense wave of research,advancing our understanding of the molecular mechanisms and pathophysiological implications of regulated necrosis ”4,5”.
molecular mechanisms、cell death、understanding、implications、traditional、would、research、multiple、work、wave
21
R329.2(人体形态学)
2011-12-23(万方平台首次上网日期,不代表论文的发表时间)
1383-1385