Essential role of DOT1L in maintaining normal adult hematopoiesis
Dear Editor,Histone methylation plays important roles in regulating gene expression and diverse biological processes ” 1 ”.Methylation of a unique residue,lysine 79 of histone H3 (H3K79),is evolutionarily conserved from yeast to human and is catalyzed by yeast Dotl (disruptor of telomeric silencing) and its mammalian homolog DOT1L (Dotl-Like),respectively ”2”.
biological processes、gene expression、unique、plays、human
21
R329.2(人体形态学)
NIH grantCA119133
2011-12-05(万方平台首次上网日期,不代表论文的发表时间)
1370-1373