Caveolar vesicles generate DNA damage and perpetuate cellular aging
@@ The replicative limit of human fibroblasts has long provided a model to assess the molecular mechanisms underlying cellular aging ”1”.In culture, fibroblasts which reach the end of their proliferative lifespan acquire profound molecular changes that limit their response to growth factors, and cause permanent exit from the cell cycle ”2”.
molecular mechanisms、growth factors、cell cycle、provided、culture、changes、reach、model、human、long、end
21
Q254(细胞生理学)
2011-12-09(万方平台首次上网日期,不代表论文的发表时间)
993-994