Reduction of follistatin-like 1 in primary afferent neurons contributes to neuropathic pain hypersensitivity
@@ Dear Editor,Nerve injury-induced neuropathic pain is difficult to treat in clinic.Lack of comprehensive understanding of the mechanism underlying such chronic pain hypersensitivity delays the development of more effective therapy.Accumulated evidence shows that peripheral nerve injury alters the expression of many neurotransmitters, receptors, ion channels and signaling molecules in the dorsal root ganglion (DRG) and the dorsal horn of spinal cord ”1”.Some of these molecular changes in the pain pathway are correlated with the current therapy for neuropathic pain.
neuropathic pain、peripheral nerve injury、dorsal root ganglion、understanding、chronic pain、spinal cord、dorsal horn、development、molecular、effective、changes、DRG
21
Q2(细胞生物学)
NNSFC30630029;30621062;MOST201 ICBA00400;2009CB522005;%%06R214160;2007KIP402
2011-07-06(万方平台首次上网日期,不代表论文的发表时间)
697-699