TET1 is a DNA-binding protein that modulates DNA methylation and gene transcription via hydroxylation of 5-methylcytosine
@@ Dear Editor,DNA methylation, which often occurs at the 5-carbon position of cytosine (5mC) located in CpG dinucleotide, is a key epigenetic hallmark and serves as a major epigenetic mechanism for establishing X-inactivation, paren tal imprinting and silencing retrotransposable elements during early embryogenesis in mammals.
via、DNA methylation、embryogenesis、elements、during、major、key、CpG
20
Q2(细胞生物学)
NIHGM078458;DK077036
2011-01-14(万方平台首次上网日期,不代表论文的发表时间)
1390-1393