Probing CENP-E function in chromosome dynamics using small molecule inhibitor syntelin

摘要：

@@ Dear Editor,Chromosome movements during mitosis are orchestrated primarily by the interaction of spindle microtubules with the kinetochore ”1”, the site for attachment of spindle microtubules to the centromere. The kinetochore has an active function in chromosomal segregation through microtubule-based motors located at or near it ”1-2”.

机标关键词：small molecule、function、interaction、during、active

所属期刊栏目：20

分类号：Q2(细胞生物学)

资助基金：This work was initiated by the chemical biology grant PGX-1 from the Proteomics Research Laboratory;supported in part by Chinese Academy of Sciences GrantsKSCX2-YW-H-10;KSCX2-YW-R195;973 projects2002CB713700;2010CB912103;National Natural Science Foundation of China90913016;Georgia Cancer Coalition Eminent Scholar Award

在线出版日期：2011-01-14（万方平台首次上网日期，不代表论文的发表时间）

页码：1386-1389