New molecular connections in angiogenesis

摘要：

@@ In vertebrates, oxygen and nutrients are delivered to tissues by the circula-tion of blood through vessels, comprised of a branched network of endothelial tubes termed the vasculature. Crucial for the formation of blood vessels during development is the process of angiogenesis, in which new sprouts form from pre-existing vessels in a complex cascade of cellular events. This involves the activation of an endothelial cell in the vessel to become a highly exploratory ”tip” cell that migrates to invade the surrounding tissues, while remaining tightly connected to the fol-lowing cells that subsequently generate the tubular structures of a new vessel.

机标关键词：molecular、endothelial cell、blood vessels、development、structures、connected、network、complex、cascade、new、during、cells、form、tip

所属期刊栏目：20

分类号：Q2(细胞生物学)

在线出版日期：2010-11-15（万方平台首次上网日期，不代表论文的发表时间）

页码：980-981