The Al-2-dependent regulator LsrR has a limited regulon in Salmonella Typhimurium

摘要：

@@ Dear Editor,Bacteria are able to communicate with each other through small, diffusible molecules. In some species,this type of communication has been linked to virulence.Therefore, bacterial cell-cell communication pathways have recently been put forward as promising targets for new anti-microbial therapeutics ”1”. Several different communication systems have been identified in bacteria,both for intraspecies and for interspecies communication.The AI-2 signal is hypothesized to be involved in interspecies bacterial communication, since it is produced by an enzyme, LuxS, which is widely conserved among Gram-negatives and Gram-positives ”2”.

机标关键词：Salmonella Typhimurium、bacterial communication、communication systems、different、type of、species、enzyme、small、AI-2、new

所属期刊栏目：20

分类号：Q2(细胞生物学)

资助基金：This work was also partially supportedGBOUSQUAD-20160;the Centre of Excellence SymBioSys Research Council KU Leuven EF/05/007 and GOA Research Council KU Leuven GOA/2008/11;M McClelland was supported in partAI034829;AI057733;;AI52237-06

在线出版日期：2010-11-23（万方平台首次上网日期，不代表论文的发表时间）

页码：966-969