A BID on mitochondria with MTCH2
@@ Apoptosis is a key process for tissue homeostasis and renewal. Its dysregulation is implicated in most human diseases, from cancer to neurodegeneration. Apoptosis is triggered by stimuli that damage the internal structures of the cell, or by specialized ”death”receptors on its surface. In certain cell types, Bid, a ”BH3-only” member of the Bcl-2 family of death regulators integrates these two pathways at the mitochondrial level. Despite years of intense research, the mechanisms by which Bid translocates to mitochondria remain unclear. A recent study by Gross and colleagues sheds new light on this process.
homeostasis、structures、death、research、cell、family、Bid、study、light、human、Bcl-2、two、new、key
20
Q2(细胞生物学)
2010-11-23(万方平台首次上网日期,不代表论文的发表时间)
863-865