A new twist in the microRNA pathway: Not Dicer but Argonaute is required for a microRNA production

摘要：

@@ Found in all metazoans, microRNAs or miRNAs are small non-coding RNA of～22 nucleotides in length that completely reshaped our understanding of gene regulation. This new class of gene regulator is mostly transcribed by the RNA polymerase Ⅱ producing a long stem-loop structure, called primary-or pri-miRNA, that will first be processed in the cell nucleus by a multiprotein complex called microprocessor to generate a shorter RNA structure called precursor-or pre-miRNA.

机标关键词：microRNA、new、structure、RNA polymerase、non-coding RNA、understanding、nucleus、complex、miRNAs、small、Found、class、long、cell

所属期刊栏目：20

分类号：Q2(细胞生物学)

在线出版日期：2010-09-28（万方平台首次上网日期，不代表论文的发表时间）

页码：735-737