Double knockouts in human embryonic stem cells
@@ Gene targeting is the method of pre-cise genome modification that utilizes the innate DNA repair mechanism in cells, known as homologous recom-bination. At its genesis, gene targeting in mouse embryonic stem (ES) cells was a breakthrough for genetics and developmental biology. Its application has enhanced researchers” ability to study gene function and model human disease, which was recognized by the Nobel Prize in Physiology or Medicine 2007.
embryonic stem cells、application、DNA repair、method of、function、genesis、study、model、human
20
Q2(细胞生物学)
2010-05-04(万方平台首次上网日期,不代表论文的发表时间)
共3页
250-252