Evidence for the involvement of ActA in maturation of the Listeria monocytogenes phagosome

摘要：

@@ Dear Editor,Listeria monocytogenes (Lm), a Gram-positive facultative bacterium, is the causative agent of listeriosis, a food-borne disease affecting humans ”1”. During infections, Lm enters phagosomes from which it escapes into the cytoplasm. Listeriolysin O (LLO) is essential, and two phospholipases play a role in this process ”1”. Actin polymerization provides the propulsive force that moves the bacteria through the cytoplasm and into adjacent cells. It is initiated by the interaction of the N-terminal domain of ActA, a 639 amino acid membrane protein, with the host Arp2/3 complex.

机标关键词：membrane protein、Listeriolysin O、interaction、amino acid、essential、During、domain、agent、Actin、two

所属期刊栏目：20

分类号：Q2(细胞生物学)

在线出版日期：2010-03-26（万方平台首次上网日期，不代表论文的发表时间）

页数：共4页

页码：109-112