A design of multi-source samples as a shared control for association studies in genetically stratified populations

摘要：

@@ Dear Editors,More and more genetic variants which contribute to human complex traits were identified recently in genome-wide association studies (GWAS), an approach that shows more efficiency than any other genetic ap-proaches ever before ”1”.It holds the promise to disclose genetic mechanism underlying the mystery of human diseases, since the most, if not all, of the genetic variants in the human genome could be investigated for their pos-sible association with diseases by comparing the frequen-cies of alleles in the cases (patients) and controls (healthy subjects).

机标关键词：association studies、controls、multi-source、genetic mechanism、human genome、approach、complex

所属期刊栏目：19

分类号：Q2(细胞生物学)

在线出版日期：2009-08-05（万方平台首次上网日期，不代表论文的发表时间）

页数：共3页

页码：913-915