Knockdown of flotillin-2 inhibits lung surfactant secretion by alveolar type Ⅱ cells

摘要：

@@ Dear Editor,Lung surfactant is stored in lamellar bodies and exocytosed following fusion of the lamellar bodies with the plasma membrane of alveolar type Ⅱ (AT2) cells ”1”.A number of proteins have been shown to be involved in surfactant secretion including SNAREs,NSF,α-SNAP and annexin A2 ”2,3”.Lipid rafts enriched in SNAREs are crucial for surfactant secretion ”4”.

机标关键词：plasma membrane

所属期刊栏目：18

分类号：Q2(细胞生物学)

资助基金：supported by the National Institute of HealthR01 HL-052146;R01 HL-071628;R01 HL-083188

在线出版日期：2008-09-01（万方平台首次上网日期，不代表论文的发表时间）

页数：共3页

页码：701-703