The aryl hydrocarbon receptor:a regulator of Th17 and Treg cell development in disease

摘要：

@@ The aryl hydrocarbon receptor (AhR)was discovered almost 30 years ago as a specific binding site for the halogenated polycyclic aromatic hydrocarbon,2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD),an environmental toxin (as reviewed in ”1”).Within the last decade,AhR was found to have a basic helixloop-helix and function as a ligand-activated transcription factor.Located in the cytoplasm of most cells,AhR forms a receptor complex with several proteins including the chaperone protein hsp90 (a 90kDa heat shock protein).

机标关键词：aryl hydrocarbon receptor、transcription factor、aromatic hydrocarbon、heat shock protein、binding site

所属期刊栏目：18

分类号：Q2(细胞生物学)

在线出版日期：2008-09-01（万方平台首次上网日期，不代表论文的发表时间）

页数：共4页

页码：605-608