A fresh look at an antiviral helicase

摘要：

@@ In order to survive,all organlsms must guard against viral infections.Recognition of viruses is accomplished via multiple sensors.Many mammalian proteins can recognize viral products,such as double-stranded RNA(dsRNA),yet feW of them are known to induce interferon,the central antiviral messenger.Since interferon is indispensable for Successful antiviral defense ”1”,the interferon-inducing sensors have been of particular interest.However,a clear understanding of such sensors has been elusive,and the first well-established sensor family,the toll-like receptors (TLRs),was described relatively recently”2”.Antiviral TLRS are positioned in the endosomes,where they report the appearance of viral genetic material(DNA,single-and double-stranded RNA).

所属期刊栏目：17

分类号：Q2(细胞生物学)

在线出版日期：2008-05-28（万方平台首次上网日期，不代表论文的发表时间）

页数：共3页

页码：898-900