Stem cells derived from testis show promise for treating a wide variety of medical conditions
@@ The continuation of the spermatogenic process throughout life relies on a proper regulation of self-renewal and differentiation of germline testis stem cells,the spermatogonial stem cells.These are single cells situated on the basal membrane of the seminiferous epithelium.Only 0.03%of all germ cells are spermatogonial stem cells(SSCs)”1-3”.To maintain spermatogenesis,the processes of self-renewal and differentiation of SSCS must be precisely regulated by intrinsic gene expression in the stem cells and extrinsic signals,including soluble factors or adhesion molecules from the surrounding microenvironment,the stem cell niche.
spermatogonial stem cells、adhesion molecules、gene expression、germ cells
17
Q2(细胞生物学)
2008-05-28(万方平台首次上网日期,不代表论文的发表时间)
共3页
895-897