Na+ Binding and pH-Dependent Transport in Nonlabens dokdonensis Rhodopsin 2
Dear editor,Light-driven Na+ pumping rhodopsins (NaRs),the next generation optogenetic tools,are a family of seven-helical transmembrane proteins and covalently link to a retinal chromophore”1”.NaRs have a putative Na+-conducting motif of Asn112-Asp116-Gln123 ”1”,homologous to the H+-conducting motif of Asp85-Thr89-Asp96 in H+ pump bacteriorhodopsin (BR)”2”.Powered by light,NaRs actively transport Na+ or H+ outward to generate electrochemical potential energy”1”.
potential energy
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P4 ;O56
grants from The National Natural Science Foundation of China21273279,31170794;the special fund for the Integration of Science and Education2015-2017;University of Chinese Academy of Sciences
2017-09-01(万方平台首次上网日期,不代表论文的发表时间)
共4页
625-628