粒度均匀的分子印迹聚合物在手性拆分和生物分析中的应用

摘要：

@@ Molecular recognition plays an important role in biological and chemical processes. Since molecular imprinting techniques can afford complementary binding sites for a target molecule, the molecularly imprinted polymer (MIP) for the target molecule has been used for its specific recognition as chromatographic media, solid-phase extraction media, artificial antibodies, membranes and sensors”1-4”. Usually, MIPs were prepared by a bulk polymerization method. However, the disadvantage of the method is that the obtained block polymers should be crushed, ground and sieved to produce high performance liquid chromatographic (HPLC) packing materials. Recently, we prepared the uniformly sized MIPs by a multi-step swelling and polymerization method”5”, which is suitable for preparing HPLC packing materials, and renders in situ modification susceptible.

机标关键词：粒度、分子印迹聚合物、手性拆分、生物分析、应用、Molecularly Imprinted Polymers、molecularly imprinted polymer、high performance liquid、molecular imprinting、bulk polymerization、chemical processes、in situ

所属期刊栏目：22

分类号：O658(分析化学)

在线出版日期：2004-09-09（万方平台首次上网日期，不代表论文的发表时间）

页数：共3页

页码：306-308