国家自然科学基金82170528;广东省自然科学基金2022A1515012254;广州市科技计划市校(院)联合资助项目202201020612;广州市临床特色技术项目2023C—TS48;National Natural Science Foundation of China82170528;Natural Science Foundation of Guangdong Province2022A1515012254;Guangzhou Science and Technology Plan of Municipal University Institute Joint Funding202201020612;Guangzhou Municipal Project of Clinical Specialty Technology2023C—TS48