国家自然科学基金青年基金81301606,成都军区总医院院管课题2013YG-B015,成都军区总医院研究型人才资助项目42412E33;This work was supported by the National Natural Science Foundation of China 81301606,the Foundation of Chengdu Military General Hospital 2013 YG-B015,and the Research Talent Project of Chengdu Military General Hospital 42412E33