青岛市市南区科技项目2014-14-011-SW;农业部东海海水健康养殖重点实验室T61201406;山东省自然科学基金项目ZR2015PC015共同资助[This work was supported by Qingdao City South District Science and Technology Project2014-14-011-SW;Key Laboratory of Healthy Mariculture for the East China Sea,Ministry of AgricultureT61201406;Natural Science Funds of Shandong Province ZR2015PC015]