Fatal graft versus host hemolytic reaction from Rhesus compatible mismatched liver transplantation
Matching for Rhesus (Rh) blood group is not part of organ allocation systems. The principle concern expressed in the literature is that Rh-negative recipients might become sensitized and produce anti-D antibody which would have consequences for them if transfusion with Rh-positive blood or a pregnancy were to occur later. While Rh allosensitization is thought to occur in over 80％of Rh-negative recipients of Rh-positive blood, Starzl reported that it is less much less common in organ (liver, heart, lung) recipients even if they received Rh-positive blood during the operation (1). A more recent review of pediatric liver transplantation confirms the very low rate of allosensitization of Rh recipients of grafts from Rh-positive donors (2). In theory, there should be no risk of rejection if the combination is reversed—Rh-negative donor to a Rh-positive recipient. Therefore, it does not appear to be necessary to consider Rh status when allocating organs for transplantation.
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2019-07-17（万方平台首次上网日期，不代表论文的发表时间）
共3页
186-188
