Gut microbiome: a key player in cancer immunotherapy
Immune checkpoint inhibitors (ICIs) have revolutionized the therapeutic approaches used to treat cancer. Immune checkpoint molecules located on tumor cells interact with receptors on cytotoxic CD8+ T cells (a type of effector T lymphocyte) and consequently lead to evasion of tumor cells from the immune system. ICIs stimulate T cellmediated antitumor immunity by inhibiting the interactions between immune checkpoint molecules and inhibitory T cell receptors.
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2019-07-16(万方平台首次上网日期,不代表论文的发表时间)
共2页
479-480