Hydrogen sulfide and nonalcoholic fatty liver disease
Nonalcoholic fatty liver disease (NAFLD) is one of the most common chronic liver disease worldwide. The septum of NAFLD ranges from simple steatosis to nonalcoholic steatohepatitis, the latter of which may further progress to liver cirrhosis and even more advanced stages in 20% patients (1,2). During last decade, nonalcoholic steatohepatitis has been identified as the most rapidly growing indication for liver transplantation in patients with hepatocellular carcinoma in the United States (3). Meanwhile, NAFLD also significantly increases risk of cardiovascular diseases, type 2 diabetes, chronic kidney disease, and colorectal neoplasia.
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This study was supported by the Key Research Development Program of Zhejiang Province2018C03018;the Traditional Chinese Medicine Scientific Research Fund Project of Zhejiang Province2017ZA079
2019-07-18(万方平台首次上网日期,不代表论文的发表时间)
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122-124