Landscape of genomic alterations in hepatocellular carcinoma:current knowledge and perspectives for targeted therapies
Hepatocellular carcinoma (HCC) is a deadly cancer worldwide characterized by a rising incidence and limited therapeutic options (1).HCC is associated with multiplerisk factors, including chronic hepatitis B and C (HBV/HCV), alcohol intake, aflatoxin B1 exposure, diabetes and obesity. In addition, liver carcinogenesis is a long
and multistep process associated with the accumulation of multiple genetic and epigenetic alterations resulting in tumor heterogeneity (1).
6
Author's laboratory is supported by funds from Inserm, University of Rennes, Institut National du Cancer, Ligue Contre le Cancercd22, cd35, cd85;Association Fran?aise pour l'Etude du Foie AFEF. KB is supported by a doctoral fellowship from Ligue Contre le Cancercd22;Conseil Régional de Bretagne
2019-07-17(万方平台首次上网日期,不代表论文的发表时间)
共4页
404-407