Resection or transplantation for hepatocellular carcinoma: is the decision clear for patients beyond Milan criteria?
Hepatocellular carcinoma (HCC) is the second leading cause of cancer related mortality worldwide, and in western countries, its incidence is on the rise (1,2). The majority of these patients have underlying liver disease and cirrhosis from hepatitis B (HBV) and/or hepatitis C (HCV), alcoholism, and non-alcoholic steatohepatitis (NASH). The standard surgical therapies, which provide the greatest hope for a cure are resection and transplantation (3,4). Unfortunately, these therapies are not without their shortcomings. Intrinsic liver dysfunction is usually present, limiting the extent of resection, a shortage of available organs limits transplantation, and frequent late detection of disease limits both (5).
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2019-07-18(万方平台首次上网日期,不代表论文的发表时间)
共3页
284-286