Is sarcopenia a prognostic factor after living donor liver transplantation?
We read with great interest the article by Kaido et al. (1) entitled "Effects of Pretransplant Sarcopenia and Sequential Changes in Sarcopenic Parameters after Living Donor Liver Transplantation," published in the journal Nutrition. The authors previously reported that the preoperative skeletal muscle mass (SMM) was significantly correlated with the branched-chain amino acid (BCAA) to tyrosine ratio and the body cell mass (2). They also found that a low preoperative SMM was an independent risk factor for mortality after a living donor liver transplantation (LDLT) (2). Therefore, they conducted this prospective clinical study to investigate the effects of pretransplant sarcopenia on survival, and to examine any sequential changes in the sarcopenic parameters after an LDLT. In this article, sarcopenia was defined by measuring the SMM and grip strength (GS). The overall survival rates after an LDLT were significantly lower in those patients with sarcopenia than in those without sarcopenia (P<0.001). Based on the recovery after an LDLT, the GS returned to the preoperative levels more smoothly than the SMM (1).
6
2019-07-18（万方平台首次上网日期，不代表论文的发表时间）
共2页
258-259
