Circulating microRNAs for early detection of hepatitis B-related hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is a major challenge for global health. Indeed, HCC represents the third leading and fastest rising cause of cancer death worldwide (1). About 90％ of HCC cases can be associated with a well-characterized underlying risk factor including chronic hepatitis B, hepatitis C, ethanol consumption, aflatoxin exposure, non-alcoholic fatty liver disease, metabolic diseases like diabetes, and hereditary liver disease (1-3). Although the risk of developing HCC can be reduced in patients by treatment of the underlying cause, e.g., by viral clearance, strategies to prevent cancer development in patients with advanced fibrosis and established cirrhosis are still lacking (4).
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The authors acknowledge grant support of the European UnionERC-2014-AdG-671231-HEPCIR, EU FP7 HepaMab, EU-Infect-ERA, Interreg IV-Rhin Supérieur-FEDER-Hepato-Regio-Net 2012, ANRS;ANRANR-10-LABX-0028_HepSYS, IHU TheraHCC
2019-07-17（万方平台首次上网日期，不代表论文的发表时间）
共3页
198-200
